Hydrochloric Acid → HCID 118431917, compound

Participants

Reaction Steps

1-(2-Chloro-phenyl)-5-{4-[4-(N-BOC-amino)-piperidin-1-yl]-phenyl}-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole (210.0 mg, 0.34 mmol) prepared in Example 330 was added to a saturated solution of hydrochloric acid in ethyl acetate (5.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 200.0 mg of the titled compound as a pale yellow solid.

Provenance & Evidence