Hydrochloric Acid → HCID 118431623, compound

Participants

Reaction Steps

1-(2-Chloro-phenyl)-5-[6-(4-BOC-piperazin-1-yl)-pyridin-3-yl]-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole (65.0 mg, 0.11 mmol) prepared in Example 355 was added to a saturated solution of hydrochloric acid in ethyl acetate (2.0 mL). The reaction mixture was stirred at room temperature for 1 hour and then concentrated under reduced pressure to give 60.0 mg of the titled compound as a yellow liquid.

Provenance & Evidence