6-(Methylsulphanyl)pyridine-3-boronic acid → 5-(2-chloro-phenyl)-1-{4-[6-(methylsulfanyl)-pyridin-3-yl]-phenyl}-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole

Participants

Reaction Steps

The titled compound was prepared in accordance with the same procedures as in Example 421, except for using 1-(4-bromo-phenyl)-5-(2-chloro-phenyl)-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole prepared in Step 5 of Preparation 24; and using 6-methylthiopyridin-3-ylboronic acid instead of 3-methylthiophenylboronic acid.

Provenance & Evidence