HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Ethoxy-5-fluorophenyl)boronic acid → ethyl 4-(2-ethoxy-5-fluorophenyl)-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Ethoxy-5-fluorophenyl)boronic acid | HCID 16217479 | — |
| Reactant | HCID 86666646 | HCID 86666646 | — |
| Product | ethyl 4-(2-ethoxy-5-fluorophenyl)-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate | HCID 67955344 | — |
Reaction Steps
Starting from ethyl 4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate (example A4) and commercially available 2-ethoxy-5-fluoro-phenyl-boronic acid the title compound is obtained as pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376442B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-46e0d4a1867a4b52bd43333dd6e018da |
| Source note | uspto-grants-2016_06 |