HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 178429360, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid | HCID 67956161 | — |
| Reactant | HCID 178418966 | HCID 178418966 | — |
| Product | HCID 178429360 | HCID 178429360 | — |
Reaction Steps
Starting from 4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.c2) and commercially available tert-butyl cis-(4-amino-cyclohexyl)-carbamate the title compound is obtained as pale yellow viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376442B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-e24c9e9e2eed4d02b9e8e25d49a5ec9a |
| Source note | uspto-grants-2016_06 |