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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2208249Generated: October 30, 2026

4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 86666665, compound

https://huagongshe.com/reaction/2208249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956012—
ReactantHCID 86666666HCID 86666666—
ProductHCID 86666665HCID 86666665—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.g1) and (1R*,2R*,4R*)-4-azido-2-fluorocyclopentanamine hydrochloride (example C45) the title compound is obtained as pale yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09376442B2
Source datasetuspto-grants-2016_06
ORD IDord-e5f01d3696f64437b5409f1716a6299e
Source noteuspto-grants-2016_06