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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2208250Generated: October 31, 2026

4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 86666668, compound

https://huagongshe.com/reaction/2208250

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956012—
ReactantHCID 131732247HCID 131732247—
ProductHCID 86666668HCID 86666668—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.g1) and tert-butyl [(1R*,2S*,4R*)-4-amino-2-fluorocyclohexyl]carbamate (example C55) the title compound is obtained as pale yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09376442B2
Source datasetuspto-grants-2016_06
ORD IDord-9c1b72f3a6d847a9883bf4a6940f5eaf
Source noteuspto-grants-2016_06