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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2208251Generated: November 3, 2026

4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 86666670, compound

https://huagongshe.com/reaction/2208251

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956012—
ReactantHCID 86666671HCID 86666671—
ProductHCID 86666670HCID 86666670—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.g1) and (1R*,2S*,4R*)-4-azido-2-fluorocyclohexanamine hydrochloride (example C56) the title compound is obtained as pale yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09376442B2
Source datasetuspto-grants-2016_06
ORD IDord-8fc2cba6b2bc4ee1a58cdcde0ce7aa42
Source noteuspto-grants-2016_06