Nitric Acid → 2-Methyl-3-nitro-5-(trifluoromethyl)benzoic acid

Participants

Reaction Conditions

Reaction Steps

2-methyl-5-(trifluoromethyl)benzoic acid (4 g, 19.6 mmol) was added to cooled conc. H2SO4 (27 mL) at −10° C. in small portions. After 10 minutes nitrating mixture {prepared by mixing conc. HNO3 (2.77 g, 44.44 mmol) with conc.H2SO4 (3.6 mL)} was added drop wise at −10° C. The resulting solution was stirred at −10° C. for 30 minutes. On completion, the reaction mixture was poured into ice cold water. The solid was filtered, washed with water and dried under vacuum to give 2-methyl-3-nitro-5-(trifluoromethyl)benzoic acid (4.95 g, 99%).

Provenance & Evidence