1,3-Dibromo-5,5-dimethylhydantoin → 5-Bromo-2-methyl-3-nitrobenzoic acid

Participants

Reaction Steps

To a mixture of 2-methyl-3-nitrobenzoic acid (15 g, 82.80 mmol) in conc. H2SO4 (60 mL), 1,3-dibromo-5,5-dimethyl-2,4-imidazolidinedione (13.07 g, 45.71 mmol) was added and reaction mixture was stirred at room temperature for 5 h. After completion of reaction, reaction mixture was slowly poured onto ice cold water (400 mL). Solid that precipitated out was filtered and dried under vacuum to obtain the desired compound (21 g, 98%).

Provenance & Evidence