1,3-Dibromo-5,5-dimethylhydantoin → 5-Bromo-2-methyl-3-nitrobenzoic acid

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Reaction Steps

To stirred solution of compound 2-methyl-3-nitrobenzoic acid (50.0 g, 276 mmol) in conc. H2SO4 (200 mL), 1,3-dibromo-5,5-dimethyl-2,4-imidazolidinedione (43.4 g, 152 mmol) was added portionwise at room temperature and stirring was continued for 5 h. On completion, the reaction mass was poured on ice cold water, the solid precipitate was filtered, washed with water and dried under vacuum giving the crude title compound (71.7 g, 99.9%) which was used without further purification.

Provenance & Evidence