HCID 70873766, compound → HCID 86719579, compound

Participants

Reaction Steps

To stirred solution of tert-butyl 3-(3-(methoxycarbonyl)-4-methyl-5-nitrophenoxy)azetidine-1-carboxylate (1.0 g, 2.7 mmol) in methanol (10 mL) was added a catalytic amount of 10% Pd/C. The mixture was stirred at room temperature under a hydrogen atmosphere (balloon pressure) for 3 hours. On completion, the reaction mixture was filtered through a celite bed which was further washed with methanol. The combined filtrates were concentrated under reduced pressure to afford the title compound (0.90 g, 98%).

Provenance & Evidence