HRID2209048

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID45091236

(4-Cyano-3-methoxyphenyl)boronic acid

C8H8BNO3

结构：C[C@@H](Oc1nc(Cl)cc2ncn(C)c12)[C@H]1CNC(=O)C1

HCID117843294

未命名化合物

PRODUCTS

生成物

结构：COc1cc(-c2cc3ncn(C)c3c(O[C@H](C)[C@H]3CNC(=O)C3)n2)ccc1C#N

HCID117843228

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID7505

Benzonitrile

C7H5N

PROCEDURE

实验过程

Following General Procedure B, beginning with (R)-4-((R)-1-(6-chloro-3-methyl-3H-imidazo[4,5-c]pyridin-4-yloxy)ethyl)pyrrolidin-2-one 2.06 (41 mg, 0.139 mmol) and 4-cyano-3-methoxyphenylboronic acid (31 mg, 0.18 mmol), 2-methoxy-4-(3-methyl-4-((R)-14(R)-5-oxopyrrolidin-3-yl)ethoxy)-3H-imidazo[4,5-c]pyridin-6-yl)benzonitrile 3B.14 was synthesized.

WORKUP

后处理

customwas synthesized