2-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-one → HCID 117843230, compound

HRID 2209202Notes

Reaction equation

HRID 2209202 reaction equation
Br[CH2:2]C(C1C=CC(OC)=C(OC)C=1)=O.ClC1C=NNC=1C(OC)=O.[Cl:25][C:26]1[CH:27]=[N:28][N:29]([CH2:35][C:36]([C:38]2[CH:43]=[CH:42][C:41]([O:44][CH3:45])=[C:40]([O:46][CH3:47])[CH:39]=2)=[O:37])[C:30]=1[C:31]([O:33][CH3:34])=[O:32]>>[Cl:25][C:26]1[CH:27]=[N:28][N:29]([CH2:35][C:36]([C:38]2[CH:43]=[CH:42][C:41]([O:44][CH3:45])=[C:40]([O:46][CH3:47])[CH:39]=2)=[O:37])[C:30]=1[C:31]([O:33][CH2:34][CH3:2])=[O:32]

Participants

4

Reactant 3

HCID 2704232-Bromo-1-(3,4-dimethoxyphenyl)ethan-1-oneHCID 7147513methyl 4-chloro-1H-pyrazole-3-carboxylateHCID 117843379HCID 117843379, compound

Product 1

HCID 117843230HCID 117843230, compound

Procedure

Following the procedure of Example 5.01, beginning with 2-bromo-1-(3,4-dimethoxyphenyl)ethanone (1.20 g, 4.63 mmol) and methyl 4-chloro-1H-pyrazole-5-carboxylate (855 mg, 5.33 mmol), methyl 4-chloro-1-(2-(3,4-dimethoxyphenyl)-2-oxoethyl)-1H-pyrazole-5-carboxylate 5.21 was synthesized.

Workup

  1. customwas synthesized

Sources & evidence

ORD record
ord-2b6c275804da4e60961d311bdeacafcd
Source dataset
uspto-grants-2016_06
Patent number
US09376441B2

Reaction notes

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