HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethyl-1,3-dihydro-indol-2-one → HCID 117842889, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethyl-1,3-dihydro-indol-2-one | HCID 313100 | — |
| Reactant | 3,3-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one | HCID 66953483 | — |
| Reactant | HCID 131735985 | HCID 131735985 | — |
| Product | HCID 117842889 | HCID 117842889 | — |
Reaction Steps
Following Steps 7 and 8 from the procedure used to prepare Example 6.53, starting from (R)-4-((R)-1-((6-chloro-3-cyclopropylpyrazolo[1,5-a]pyridin-4-yl)oxy)ethyl)pyrrolidin-2-one 6.53a (55 mg) and 3,3-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one, 13 mg of 6-(3-cyclopropyl-4-4R)-1-((R)-5-oxopyrrolidin-3-yl)ethoxy)pyrazolo[1,5-a]pyridin-6-yl)-3,3-dimethylindolin-2-one was synthesized.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376441B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-971f21ade6b24199a170cfce3c55a7f4 |
| Source note | uspto-grants-2016_06 |