HCID 117843549, compound → HCID 131735974, compound

HRID 2209276Notes

Reaction equation

HRID 2209276 reaction equation
[CH2:1]([Sn:5]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:25][CH2:26][CH2:27][CH3:28])[C:6]1[N:11]=[CH:10][C:9]([N:12]2[CH2:17][CH2:16][N:15](C(OC(C)(C)C)=O)[CH2:14][CH2:13]2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].BrC1N=CC(N2CCN([CH:46]3[CH2:49][O:48][CH2:47]3)CC2)=CC=1>>[O:48]1[CH2:49][CH:46]([N:15]2[CH2:14][CH2:13][N:12]([C:9]3[CH:10]=[N:11][C:6]([Sn:5]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:1][CH2:2][CH2:3][CH3:4])=[CH:7][CH:8]=3)[CH2:17][CH2:16]2)[CH2:47]1

Participants

3

Reactant 2

HCID 117843549HCID 117843549, compoundHCID 131735986HCID 131735986, compound

Product 1

HCID 131735974HCID 131735974, compound

Procedure

Following the procedure described for intermediate 7.14, starting from 1-(6-bromopyridin-3-yl)-4-(oxetan-3-yl)piperazine (1.78 g, 5.97 mmol), 1.78 g of 1-(oxetan-3-yl)-4-(6-(tributylstannyl)pyridin-3-yl)piperazine 7.16 was obtained. LCMS [M+H]+: 510.07.

Sources & evidence

ORD record
ord-6848a52249a843c98d66ca4a730b741d
Source dataset
uspto-grants-2016_06
Patent number
US09376441B2

Reaction notes

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