HuagongsheHuagongshe Chemistry Print Report · For research reference only
AE-646/11813021 → carboxycubane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | AE-646/11813021 | HCID 429365 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | carboxycubane | HCID 10997192 | — |
Reaction Steps
Cubanecarboxylic acid (53578-15-7) (33) is obtained from (32) by the method of Eaton and Cole, by refluxing the ketal in 25% aqueous KOH overnight. Extraction with methylene chloride, drying over magnesium sulfate, stripping the solvent, and recrystallization from pentane yields (33), mp 154°-155° C.; λmax (CCl4) 5.91μ; proton NMR (CCl4, ppm τ): -2.2(1H, s) , and 5.6-6.2(7H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05455072 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-c34a073fbaf949b88af1c3323fe69644 |
| Source note | uspto-grants-1995_10 |