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HRID220943

反应详情

EQUATION

反应方程式

HRID 220943 的结构方程式

REACTANTS

反应物

2
结构：C1COCCO1.Cl
HCID20443148

1,4-Dioxane hydrochloride

C4H9ClO2

结构：Cn1ncc2c1Nc1ccccc1N(C(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1F)C2
HCID136128389

未命名化合物

PRODUCTS

生成物

1
结构：Cl.Cn1ncc2c1Nc1ccccc1N(C(=O)c1ccc(CN)cc1F)C2
HCID136346643

未命名化合物

收率 97%

PROCEDURE

实验过程

[3-Fluoro-4-(3-methyl-4,10-dihydro-3H-2,3,4,9-tetraaza-benzo[f]azulene-9-carbonyl)-benzyl]-carbamic acid tert-butyl ester from Example E90.1 (1.25 g, 2.8 mmol) was re-acted with 4N HCl/dioxan using an analogous procedure to that described for Example E4.2 to yield the title compound (11.0 g, 97%).