3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 4-Benzyl-2-(3-chloro-4-fluorophenyl)-aniline

HRID 2209469Notes

Reaction equation

HRID 2209469 reaction equation
[CH2:1]([C:8]1[CH:14]=[CH:13][C:11]([NH2:12])=[C:10](Br)[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][C:22]=1[F:23]>>[CH2:1]([C:8]1[CH:14]=[CH:13][C:11]([NH2:12])=[C:10]([C:19]2[CH:20]=[CH:21][C:22]([F:23])=[C:17]([Cl:16])[CH:18]=2)[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 193811412-Bromo-4-benzylaniline

Product 1

HCID 193811384-Benzyl-2-(3-chloro-4-fluorophenyl)-aniline

Procedure

4-benzyl-2-bromo-aniline and 3-chloro-4-fluorobenzene boronic acid were combined to form 4-benzyl-2-(3-chloro-4-fluorophenyl)-aniline,

Sources & evidence

ORD record
ord-570525671c7d4a43af722d8a850d23b8
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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