Glycerol → 8-Bromo-6-methylquinoline

HRID 2209488Notes

Reaction equation

HRID 2209488 reaction equation
[Br:1][C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:3]=1[NH2:4].O[CH2:11][CH:12]([CH2:14]O)O>>[CH3:9][C:7]1[CH:6]=[C:5]2[C:3](=[C:2]([Br:1])[CH:8]=1)[N:4]=[CH:14][CH:12]=[CH:11]2

Participants

3

Reactant 2

HCID 753GlycerolHCID 114222-Bromo-4-methylaniline

Product 1

HCID 130880438-Bromo-6-methylquinoline

Procedure

2-bromo-4-methylaniline and glycerol can be combined to form 6-methyl-8-bromoquinoline,

Sources & evidence

ORD record
ord-9e7b6d2fa9ce47a09cf0721abe4dc62c
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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