Glycerol → 6-(n-Butyl)-8-bromoquinoline

HRID 2209491Notes

Reaction equation

HRID 2209491 reaction equation
[Br:1][C:2]1[CH:8]=[C:7]([CH2:9][CH2:10][CH2:11][CH3:12])[CH:6]=[CH:5][C:3]=1[NH2:4].O[CH2:14][CH:15]([CH2:17]O)O>>[CH2:9]([C:7]1[CH:6]=[C:5]2[C:3](=[C:2]([Br:1])[CH:8]=1)[N:4]=[CH:17][CH:15]=[CH:14]2)[CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 753GlycerolHCID 193811342-Bromo-4-butylbenzenamine

Product 1

HCID 193812156-(n-Butyl)-8-bromoquinoline

Procedure

2-bromo-4-(n-butyl)aniline and glycerol can be combined to form 6-(n-butyl)-8-bromoquinoline,

Sources & evidence

ORD record
ord-80679c6c067f4cb9a687b3d5e1838cb1
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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