Glycerol → 8-Bromo-6-[(methanesulfonyl)methyl]quinoline

HRID 2209495Notes

Reaction equation

HRID 2209495 reaction equation
[Br:1][C:2]1[CH:8]=[C:7]([CH2:9][S:10]([CH3:13])(=[O:12])=[O:11])[CH:6]=[CH:5][C:3]=1[NH2:4].O[CH2:15][CH:16]([CH2:18]O)O>>[CH3:13][S:10]([CH2:9][C:7]1[CH:6]=[C:5]2[C:3](=[C:2]([Br:1])[CH:8]=1)[N:4]=[CH:18][CH:16]=[CH:15]2)(=[O:12])=[O:11]

Participants

3

Reactant 2

HCID 753GlycerolHCID 19381190HCID 19381190, compound

Product 1

HCID 98793738-Bromo-6-[(methanesulfonyl)methyl]quinoline

Procedure

2-bromo-4-(methylsulfonylmethyl)aniline and glycerol can be combined to form 6-(methylsulfonylmethyl)-8-bromoquinoline.

Sources & evidence

ORD record
ord-808e72b9f78d4137b242c49a65d0b845
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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