(3-Chlorophenyl)boronic acid → 6-(n-Butyl)-8-(3-chlorophenyl)quinoline

HRID 2209499Notes

Reaction equation

HRID 2209499 reaction equation
[CH2:1]([C:5]1[CH:6]=[C:7]2[C:12](=[C:13](Br)[CH:14]=1)[N:11]=[CH:10][CH:9]=[CH:8]2)[CH2:2][CH2:3][CH3:4].[Cl:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][CH:22]=1>>[CH2:1]([C:5]1[CH:6]=[C:7]2[C:12](=[C:13]([C:21]3[CH:20]=[CH:19][CH:18]=[C:17]([Cl:16])[CH:22]=3)[CH:14]=1)[N:11]=[CH:10][CH:9]=[CH:8]2)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 2734323(3-Chlorophenyl)boronic acidHCID 193812156-(n-Butyl)-8-bromoquinoline

Product 1

HCID 193811926-(n-Butyl)-8-(3-chlorophenyl)quinoline

Procedure

6-(n-butyl)-8-bromoquinoline and 3-chlorobenzene boronic acid can be combined to form 6-(n-butyl)-8-(3-chlorophenyl)quinoline,

Sources & evidence

ORD record
ord-6c53db12a2484e3db3814c69706d3e84
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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