3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → HCID 19381189, compound

HRID 2209503Notes

Reaction equation

HRID 2209503 reaction equation
[CH:1]1([CH2:6][C:7]2[CH:8]=[C:9]3[C:14](=[C:15](Br)[CH:16]=2)[N:13]=[CH:12][CH:11]=[CH:10]3)[CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:18][C:19]1[CH:20]=[C:21](B(O)O)[CH:22]=[CH:23][C:24]=1[F:25]>>[CH:1]1([CH2:6][C:7]2[CH:8]=[C:9]3[C:14](=[C:15]([C:21]4[CH:22]=[CH:23][C:24]([F:25])=[C:19]([Cl:18])[CH:20]=4)[CH:16]=2)[N:13]=[CH:12][CH:11]=[CH:10]3)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 19381137HCID 19381137, compound

Product 1

HCID 19381189HCID 19381189, compound

Procedure

6-(cyclopentylmethyl)-8-bromoquinoline and 3-chloro-4-fluorobenzene boronic acid can be combined to form 6-(cyclopentylmethyl)-8-(3-chloro-4-fluorophenyl)quinoline,

Sources & evidence

ORD record
ord-d0a9317a6b9d4608a20ece92475b98e6
Source dataset
uspto-grants-1995_10
Patent number
US05455252

Reaction notes

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