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HRID220953

反应详情

EQUATION

反应方程式

HRID 220953 的结构方程式

REACTANTS

反应物

2
结构：C1COCCO1.Cl
HCID20443148

1,4-Dioxane hydrochloride

C4H9ClO2

结构：Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CNC(=O)OC(C)(C)C)c(F)c1
HCID136128399

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CN)c(F)c1.Cl
HCID135736009

未命名化合物

收率 99%

PROCEDURE

实验过程

[4-(3,6-Dimethyl-4,10-dihydro-3H-2,3,4,9-tetraaza-benzo[f]azulene-9-carbonyl)-2-fluoro-benzyl]-carbamic acid tert-butyl ester from Example E98.1 (1.29 g, 2.8 mmol) was reacted with 4N HCl/dioxan using an analogous procedure to that described for Example E4.2 to yield the title compound (1.1 g, 99%).