HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → (9S, 10S)-2-Chloro-9,10-dihydro-9,10-methano-9-anthracenecarbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (9S,10S)-2-chloro-9,10-dihydro-9,10-methano-9-anthracenecarboxylic acid | HCID 67637562 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (9S, 10S)-2-Chloro-9,10-dihydro-9,10-methano-9-anthracenecarbonyl chloride | HCID 57139020 | 100.3% |
Reaction Steps
To a stirred suspension of (9S, 10S)-2-chloro-9,10-dihydro-9,10-methano-9-anthracenecarboxylic acid (1.0 g, 3.62 mmol), prepared as described in Example 109a, in toluene (10 mL) was added thionyl chloride (0.29 mL, 3.98 mmol). After refluxing for 1.5 h, the mixture was concentrated to give the title compound as a light yellow solid (1.05 g, quant.); MS(CI): 289 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05455246 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-a462e78a8c5941c2bb4bb1ab41df553e |
| Source note | uspto-grants-1995_10 |