Platinum(2+) → HCID 38904, compound

HRID 2209613Notes

Reaction equation

[CH2:1]1[CH2:4][C:3]2([C:10](=[O:11])[O:9][Pt:8]([NH3])([NH3:12])[O:7][C:5]2=[O:6])[CH2:2]1.[Pt+2]>>[CH2:1]1[CH2:4][C:3]([C:10]([OH:11])=[O:9])([C:5]([OH:7])=[O:6])[CH2:2]1.[NH3:12].[NH3:12].[Pt:8]

Participants

Reactant 2

HCID 105166Platinum(2+)

HCID 10339178Carboplatin

Product 1

HCID 38904HCID 38904, compound

Procedure

The acid or one or more salts are added to solutions of carboplatin or other malonato platinum(II) compounds in quantities sufficient to yield final CBDCA concentrations of about 0.25 to about 4 mg/ml at a pH of about 4 to about 8. Preferred quantities are about 1 to about 2 mg/ml.

Sources & evidence

ORD record: ord-10fba82f450e4468b6e6029589c95c4c
Source dataset: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05455270

Reaction notes

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