Ethanol hydrochloride → HCID 22906480, compound

Participants

Reaction Steps

2.30 g of 7-(1-ethylpropoxy)-5-hydroxy-2-{4-[4-(4-methylpiperazinomethyl)benzoyloxy]phenylthio}-6-methoxychromone was dissolved in 30 ml ether, 20% hydrochloric acid-ethanol was added, and the solution was stirred over 20 min., under cooling on ice. The resulting crystals were collected by filtration and dried, whereby 2.35 g of 7-(1-ethylpropoxy)-5-hydroxy-2-{4-[4-(4-methylpiperazinomethyl)benzoyloxy]phenylthio }-6-methoxychromone dihydrochloride with the following physicochemical properties was obtained.

Provenance & Evidence