Cyclopropylamine → HCID 178482888, compound

HRID 2209767Notes

Reaction equation

[C:1]([O:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][C:17](=O)[CH2:16][CH2:15]2)=[C:10]([CH2:21][NH:22][CH3:23])[CH:9]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:24]1([NH2:27])[CH2:26][CH2:25]1>>[C:1]([O:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([C@H:14]2[CH2:19][CH2:18][C@H:17]([NH:27][CH:24]3[CH2:26][CH2:25]3)[CH2:16][CH2:15]2)=[C:10]([CH2:21][NH:22][CH3:23])[CH:9]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 69828Cyclopropylamine

HCID 67847118HCID 67847118, compound

Product 1

HCID 178482888HCID 178482888, compound

Procedure

from 4-(4-tert.butoxycarbonyl-methylaminomethylphenyl)-cyclohexanone and cyclopropylamine. Colourless oil. Rf value: 0.51 (alumina, petroleum ether/ethyl acetate=4:1, v:v).

Sources & evidence

ORD record: ord-ef2643c599c74a349df5861710f1409e
Source dataset: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05455273

Reaction notes

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