HCID 53909576, compound → HCID 178482897, compound

HRID 2209796Notes

Reaction equation

HRID 2209796 reaction equation
[C:1]([O:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([C@H:14]2[CH2:19][CH2:18][C@H:17]([NH:20][CH3:21])[CH2:16][CH2:15]2)=[C:10]([CH2:22][NH:23][CH3:24])[CH:9]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:25]1([CH:31]=[CH:32][CH2:33][C:34](Cl)=[O:35])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:1]([O:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([C@H:14]2[CH2:15][CH2:16][C@H:17]([N:20]([CH3:21])[C:34](=[O:35])[CH2:33][CH:32]=[CH:31][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH2:18][CH2:19]2)=[C:10]([CH2:22][NH:23][CH3:24])[CH:9]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 53909576HCID 53909576, compoundHCID 178482895HCID 178482895, compound

Product 1

HCID 178482897HCID 178482897, compound

Procedure

from trans-4-(4-tert.butoxycarbonyl-methylaminomethylphenyl)-N-methylcyclohexylamine and 4-phenyl-3-butenoylchloride. Colourless oil. Rf value: 0.5 (silica gel, petroleum ether/ethyl acetate=1:1, v:v).

Sources & evidence

ORD record
ord-b68a8cbda9cb43d1a6cdbf2e599d0c19
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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