HCID 53909576, compound → HCID 178482891, compound

HRID 2209798Notes

Reaction equation

HRID 2209798 reaction equation
[CH2:1]([NH:8][C@H:9]1[CH2:14][CH2:13][C@H:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])=[CH:17][C:16]=2[CH2:28][NH:29][CH3:30])[CH2:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:31]1([CH:37]=[CH:38][CH2:39][C:40](Cl)=[O:41])[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:1]([N:8]([C@H:9]1[CH2:14][CH2:13][C@H:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][C:24]([CH3:26])([CH3:27])[CH3:25])=[O:22])=[CH:17][C:16]=2[CH2:28][NH:29][CH3:30])[CH2:11][CH2:10]1)[C:40](=[O:41])[CH2:39][CH:38]=[CH:37][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 53909576HCID 53909576, compoundHCID 178482889HCID 178482889, compound

Product 1

HCID 178482891HCID 178482891, compound

Procedure

from trans-N-benzyl-4-(4-tert.butoxycarbonyl-methylaminomethylphenyl)cyclohexylamine and 4-phenyl-3-butenoylchloride. Colourless oil. Rf value: 0.26 (alumina, petroleum ether/ethyl acetate/methanol=10:10:1, v:v:v).

Sources & evidence

ORD record
ord-31cd27fa8d3b46839a60669b7ed309b8
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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