3-Bromo-1-propanol → HCID 178482770, compound

HRID 2209808Notes

Reaction equation

HRID 2209808 reaction equation
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([C:6]([N:8]([C@H:12]2[CH2:17][CH2:16][C@H:15](C3C=CC(CNC)=CC=3)[CH2:14][CH2:13]2)[CH:9]2[CH2:11][CH2:10]2)=[O:7])=[CH:4][CH:3]=1.Br[CH2:30][CH2:31][CH2:32][OH:33]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([N:8]([C@H:12]2[CH2:17][CH2:16][C@H:15]([C:4]3[CH:3]=[CH:2][C:28]([CH2:30][CH2:31][CH2:32][OH:33])=[CH:27][C:5]=3[CH2:6][NH:8][CH3:9])[CH2:14][CH2:13]2)[CH:9]2[CH2:10][CH2:11]2)=[O:7])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 123083-Bromo-1-propanolHCID 178482785HCID 178482785, compound

Product 1

HCID 178482770HCID 178482770, compound

Procedure

from trans-N-(4-chlorobenzoyl)-N-cyclopropyl-4-(4-methylaminomethylphenyl)cyclohexylamine and 3-bromo-1-propanol. Melting point: 118°-123° C.

Sources & evidence

ORD record
ord-06b756c2967d47a98cabe89260b33cf3
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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