Acetyl chloride → HCID 178482773, compound

HRID 2209813Notes

Reaction equation

HRID 2209813 reaction equation
[C:1]([N:4]([C@H:12]1[CH2:17][CH2:16][C@H:15]([C:18]2[CH:23]=[CH:22][C:21]([CH2:24][CH2:25][CH2:26][OH:27])=[CH:20][C:19]=2[CH2:28][NH:29][CH3:30])[CH2:14][CH2:13]1)[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)(=[O:3])[CH3:2].[C:31](Cl)(=[O:33])[CH3:32]>>[C:31]([O:27][CH2:26][CH2:25][CH2:24][C:21]1[CH:22]=[CH:23][C:18]([C@H:15]2[CH2:16][CH2:17][C@H:12]([N:4]([C:1](=[O:3])[CH3:2])[CH2:5][C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=3)[CH2:13][CH2:14]2)=[C:19]([CH2:28][NH:29][CH3:30])[CH:20]=1)(=[O:33])[CH3:32]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 178482763HCID 178482763, compound

Product 1

HCID 178482773HCID 178482773, compound

Procedure

from trans-N-acetyl-N-benzyl-4-[4-(3-hydroxypropyl)-methylaminomethylphenyl]cyclohexylamine and acetylchloride. Oil. Rf value: 0.67 (alumina, ethyl acetate/petroleum ether=1:1, v:v).

Sources & evidence

ORD record
ord-b153d3a8ca524decb3422a9d4fb76164
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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