4-Chloro-3-methylbenzoyl chloride → HCID 178482767, compound

HRID 2209819Notes

Reaction equation

HRID 2209819 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C@H:11]2[CH2:16][CH2:15][C@H:14]([NH:17][CH3:18])[CH2:13][CH2:12]2)=[C:7]([CH2:19][NH:20][CH3:21])[CH:6]=1.[Cl:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][C:24]=1[CH3:32]>>[Cl:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([N:17]([C@H:14]2[CH2:13][CH2:12][C@H:11]([C:8]3[CH:9]=[CH:10][C:5]([CH2:4][CH2:3][CH2:2][OH:1])=[CH:6][C:7]=3[CH2:19][NH:20][CH3:21])[CH2:16][CH2:15]2)[CH3:18])=[O:28])=[CH:25][C:24]=1[CH3:32]

Participants

3

Reactant 2

HCID 130583754-Chloro-3-methylbenzoyl chlorideHCID 178482764HCID 178482764, compound

Product 1

HCID 178482767HCID 178482767, compound

Procedure

from trans-4-[4-(3-hydroxypropyl)methylaminomethyl-phenyl]-N-methylcyclohexylamine and 4-chloro-3-methylbenzoylchloride. Melting point: 98°-100° C.

Sources & evidence

ORD record
ord-9f95c7c717954dbaab2b268313b0f53d
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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