HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dichloropentane → 1-(Chloromethyl)-1-(4-fluorophenyl)-1-silacyclohexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dichloropentane | HCID 12353 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | Chloromethyldichloro(4-fluorophenyl)silane | HCID 19382008 | — |
| Product | 1-(Chloromethyl)-1-(4-fluorophenyl)-1-silacyclohexane | HCID 19382019 | 48.1% |
Reaction Steps
In the same apparatus and procedures as Example 1-i) were reacted 6.2 g of 1,5-dichloropentane (0.044 mol) and 2.8 g of magnesium species (0.11 mol), and then followed by coupling with 5.6 g (0.03 mol) of (chloromethyl)dichloro (4-fluorophenyl)silane prepared from the above procedure i) to give 3.5 g of 1-(chloromethyl)-1-(4-fluorophenyl)-1-silacyclohexane (74° C./0.2 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05455356 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-874234a9af254a279945217d395266b6 |
| Source note | uspto-grants-1995_10 |