Triethylamine → Silane, [(4-bromophenyl)methoxy](1,1-dimethylethyl)diphenyl-

Participants

Reaction Steps

To a stirred solution of 7.48 g (40 mmoles) of p-bromobenzyl alcohol and 6.07 g (60 mmoles) of triethylamine in 70 mL of sieve dried DMF at 0° C. was added 14.3 g (52 mmoles) of neat t-butyldiphenyl-silylchloride. The ice-water bath was removed and the mixture was stirred further for 20 hours. The mixture was partitioned between ether, ice-water, and 2N hydrochloric acid, and the organic phase was separated, washed with water and brine, dried over anhydrous sodium sulfate, filtered, and evaporated.

Provenance & Evidence