HCID 19381687, compound → HCID 19381608, compound

HRID 2209870Notes

Reaction equation

HRID 2209870 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[C:13]([NH:15][C:16]([C:18]2[CH:23]=[CH:22][C:21]([O:24]CC3C=CC=CC=3)=[CH:20][CH:19]=2)=[O:17])[CH:12]=[C:11](Cl)[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(Cl)Cl.CO>[CH2:1]([NH:8][C:9]1[CH:14]=[C:13]([NH:15][C:16]([C:18]2[CH:19]=[CH:20][C:21]([OH:24])=[CH:22][CH:23]=2)=[O:17])[CH:12]=[CH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 19381687HCID 19381687, compound

Product 1

HCID 19381608HCID 19381608, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Rf value: 0.58 (silica gel; methylene chloride/methanol=9:1) by hydrogenation of 4-[(2-benzylamino-6-chloro-4-pyridyl)aminocarbonyl]-1-benzyloxy-benzene at ambient temperature.

Workup

  1. customat ambient temperature

Sources & evidence

ORD record
ord-68fe3dd6689f4b538d84bcc2b66b39ee
Source dataset
uspto-grants-1995_10
Patent number
US05455348

Reaction notes

Loading…