HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2209973Generated: November 2, 2026
Nitric Acid → 4-(2-bromoethyl)-6-nitro-2(1H)-quinolinone
https://huagongshe.com/reaction/2209973
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-(2-Bromoethyl)quinolin-2(1H)-one | HCID 13471505 | — |
| Product | 4-(2-bromoethyl)-6-nitro-2(1H)-quinolinone | HCID 19379721 | — |
Reaction Steps
To a mixture of nitric acid (60%) (21 ml) and concentrated sulfuric acid (14 ml) was added 4-(2-bromoethyl)-2(1H)-quinolinone (II-2) (3.5 g, 13.9 mmol) under ice-cooling and then the mixture was stirred at 45 ° C. (bath temperature) for 45 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05457099 |
|---|
| Source dataset | uspto-grants-1995_10 |
|---|
| ORD ID | ord-aeed1175122d4bd6a70bc7a0e7970c79 |
|---|
| Source note | uspto-grants-1995_10 |
|---|
