Thionyl Chloride → HCID 19035209, compound

HRID 2209985Notes

Reaction equation

HRID 2209985 reaction equation
[F:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[C:9]([F:15])[CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:18])=O>>[F:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[C:9]([F:15])[CH:8]=[CH:7][C:3]=1[C:4]([Cl:18])=[O:5]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 97945292,4-difluoro-3-(trifluoromethyl)benzoic Acid

Product 1

HCID 19035209HCID 19035209, compound

Conditions

Temperature
50 °C

Procedure

19.3 g (0.085 mol) of 2,4-difluoro-3-trifluoromethylbenzoic acid are added in portions at room temperature to 130 ml of thionyl chloride. After metering has ended, the mixture is heated at 50° C. until the evolution of gas has ceased. The excess thionyl chloride is then removed by distillation and the crude product is reacted further directly.

Workup

  1. customThe excess thionyl chloride is then removed by distillation
  2. customthe crude product is reacted further directly

Sources & evidence

ORD record
ord-2f5d5cf8c6624651ad1aacee2d8e1d7a
Source dataset
uspto-grants-1995_10
Patent number
US05457104

Reaction notes

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