HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethyl methyl ether → 6-(2-Methoxyethylamino)-4-(3'-methylanilino)quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | 153436-70-5 | HCID 10220590 | — |
| Product | 6-(2-Methoxyethylamino)-4-(3'-methylanilino)quinazoline | HCID 19963162 | 20% |
Reaction Steps
Using an analogous procedure to that described in Example 16, 6-amino-4-(3'-methylanilino)quinazoline was reacted with 2-bromoethyl methyl ether to give 6-(2-methoxyethylamino)-4-(3'-methylanilino)quinazoline in 20% yield, m.p. 163°-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05457105 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-ccbbc5ef468947ad9180e2a69a3d52e0 |
| Source note | uspto-grants-1995_10 |