7-(phenylmethoxy)-8-(3-phenylpropyl)-4H-1-benzopyran-4-one → HCID 15296555, compound

Participants

Reaction Steps

Catalytic hydrogenation of 7-(phenylmethoxy)-8-(3-phenylpropyl)-4H-1-benzopyran-4-one, from the preceding example, was carried out over 10% palladium on carbon at room temperature and 1 atmosphere, in 1:1 methanol-ethyl acetate. The crude product was purified by chromatography on silica gel, eluting with ether-dichloromethane mixtures. The title compound, a colorless solid, mp 110°-112° C. (recrystallized from hexane-ether), was obtained in 44.9% yield.

Provenance & Evidence