HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Methoxypyridin-3-yl)boronic acid → 1-(beta-D-glucopyranosyl)-4-chloro-3-(5-(6methoxy-3-pyridyl)-2-thienylmethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Methoxypyridin-3-yl)boronic acid | HCID 2734368 | — |
| Reactant | 1-(2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5bromo-2-thienylmethyl)-4-chlorobenzene | HCID 60041289 | — |
| Product | 1-(beta-D-glucopyranosyl)-4-chloro-3-(5-(6methoxy-3-pyridyl)-2-thienylmethyl)benzene | HCID 66607410 | — |
Reaction Steps
1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-(5-bromo-2-thienylmethyl)-4-chlorobenzene 71 obtained in Example 128-(4) and 6-methoxypyridine-3-boronic acid were treated in a manner similar to Example 168 to give the target compound. APCI-Mass m/Z 478/480 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202984B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-0d1ead0bbe744e3990601a87a1e82eaf |
| Source note | uspto-grants-2012_06 |