関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 1-(2,5-Dimethyl-1,3-oxazol-4-yl)ethan-1-one | HCID 14738583 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Bromo-1-(2,5-dimethyloxazol-4-yl)ethanone | HCID 14076232 | — |
反応手順
2.8 g (0.02 mol) of 2,5-Dimethyl-4-acetyl-oxazole are dissolved in 30 ml of glacial acetic acid, and 3 ml of a 35% strength solution of hydrogen bromide in glacial acetic acid are added. The mixture is heated to 100° C. and, over the course of 1 hour, a solution of 3.2 g (0.02 mol) of bromine in 10 ml of glacial acetic acid is added. After a further 2 hours the solvent is removed, and the residue is triturated with 50 ml of ether and filtered off with suction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05457205 |
|---|
| 出典データセット | uspto-grants-1995_10 |
|---|
| ORD ID | ord-723e45e462f54b15bf2716eafa575561 |
|---|
| 出典メモ | uspto-grants-1995_10 |
|---|
