HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(2-aminopropyl)benzoate → N-[2-(4-Carbomethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(2-aminopropyl)benzoate | HCID 15034329 | — |
| Reactant | 2-Bromo-1-(thiazol-4-yl)ethanone | HCID 19974172 | — |
| Product | N-[2-(4-Carbomethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamine | HCID 19380205 | — |
Reaction Steps
Prepared analogously to Example 3 by reaction of 2-(4-carbomethoxyphenyl)-1-methylethylamine with 4-bromoacetyl-thiazole, followed by reduction and purification of the base on a silica gel plate using ethyl acetate/methanol =8:2 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05457205 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-e887a9edc56c43fa8726e4c03bf109b8 |
| Source note | uspto-grants-1995_10 |