HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Tributylstannyl)pyrimidine → 1-(beta-D-glucopyranosyl)-3-(5-(2-pyrimidinyl)-2-thienyl-methyl)-4-methoxylnaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Tributylstannyl)pyrimidine | HCID 2763251 | — |
| Reactant | 1-(4-ethylbenzyl)-5-bromopyridin-2(1H)-one | HCID 58242500 | — |
| Reactant | 1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-3-(5-bromo-2-thienylmethyl)-4-methoxylnaphthalene | HCID 66607611 | — |
| Product | 1-(beta-D-glucopyranosyl)-3-(5-(2-pyrimidinyl)-2-thienyl-methyl)-4-methoxylnaphthalene | HCID 67157890 | — |
Reaction Steps
1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-3-(5-bromo-2-thienylmethyl)-4-methoxynaphthalene obtained in Example 265-(3) and 2-tributylstannylpyrimidine were treated in a manner similar to Example 128-(5) and (6) to give 1-(β-D-glucopyranosyl)-3-(5-(2-pyrimidinyl)-2-thienylmethyl)-4-methoxynaphthalene. APCI-Mass m/Z 495 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202984B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-c45db7a1bfcb44aaae9253431652f2a4 |
| Source note | uspto-grants-2012_06 |