Sodium Hydroxide → HCID 19974292, compound

HRID 2210394Notes

Reaction equation

HRID 2210394 reaction equation
[C:1]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([NH:16][CH2:17][CH:18]([OH:25])[C:19]2[N:20]=[C:21]([Cl:24])[S:22][CH:23]=2)[CH3:15])=[CH:9][CH:8]=1)([O:3]C)=[O:2].[OH-].[Na+]>CO>[C:1]([CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][CH:14]([NH:16][CH2:17][CH:18]([OH:25])[C:19]2[N:20]=[C:21]([Cl:24])[S:22][CH:23]=2)[CH3:15])=[CH:11][CH:12]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19974165HCID 19974165, compound

Product 1

HCID 19974292HCID 19974292, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared by analogy to Example 97 by reaction of N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-chloro-thiazol-4-yl)ethanamine with 1N sodium hydroxide solution in methanol

Sources & evidence

ORD record
ord-c0cf9f491f984e0bb41585f137c86ef6
Source dataset
uspto-grants-1995_10
Patent number
US05457205

Reaction notes

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