2-Propylthiophene → 5-Bromo-2-methoxy-1-(5-n-propyl-2-thienylmethyl)benzene

HRID 221053Notes

Reaction equation

HRID 221053 reaction equation
[CH2:1]([C:4]1[S:5][CH:6]=[CH:7][CH:8]=1)[CH2:2][CH3:3].[Br:9][C:10]1[CH:11]=[CH:12][C:13]([O:18][CH3:19])=[C:14]([CH:17]=1)[CH:15]=O>>[Br:9][C:10]1[CH:11]=[CH:12][C:13]([O:18][CH3:19])=[C:14]([CH2:15][C:6]2[S:5][C:4]([CH2:1][CH2:2][CH3:3])=[CH:8][CH:7]=2)[CH:17]=1

Participants

3

Reactant 2

HCID 737712-PropylthiopheneHCID 906845-Bromo-2-methoxybenzaldehyde

Product 1

HCID 666083775-Bromo-2-methoxy-1-(5-n-propyl-2-thienylmethyl)benzene

Procedure

2-n-Propylthiophene and 5-bromo-2-methoxybenzaldehyde were used and treated in a manner similar to Reference Example 7 to give the target compound. APCI-Mass m/Z 325/327 (M+H).

Workup

  1. additiontreated in a manner similar to Reference Example 7
  2. customto give the target compound

Sources & evidence

ORD record
ord-fac1604192c34f9183d011aeda674123
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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