Benzoyl Peroxide → HCID 19378967, compound

HRID 2210584Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[C:14]([C:16]2[N:17]=[N:18][N:19]([C:21]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:20]=2)=[O:15])=[CH:4][CH:3]=1.[Br:40]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[Br:40][CH2:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[C:14]([C:16]2[N:17]=[N:18][N:19]([C:21]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)([C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=3)[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:20]=2)=[O:15])=[CH:6][CH:7]=1

Participants

Reactant 3

HCID 7187Benzoyl Peroxide

HCID 67184N-bromobutanimide

HCID 19378971HCID 19378971, compound

Product 1

HCID 19378967HCID 19378967, compoundYield 100.6%

Procedure

400 mg of 4'-methyl-2-(2-trityltetrazol-5-ylcarbonyl)biphenyl (prepared as described in Preparation 12), 150 mg of N-bromosuccinimide and 20 mg of benzoyl peroxide were treated in the same manner as described in Preparation 8, to give 465 mg of the title compound as a crystalline powder, melting at 161°-163° C. (with decomposition).

Workup

customas described in Preparation 8

Sources & evidence

ORD record: ord-79971cea39f84196b6d5eed9e6bb6d78
Source dataset: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05459148

Reaction notes

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