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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2210669Generated: October 31, 2026

Hydrochloric Acid → 6-Chloro-3-pyridinecarbonitrile

https://huagongshe.com/reaction/2210669

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 57255702HCID 57255702—
Product6-Chloro-3-pyridinecarbonitrileHCID 5152094—

Reaction Steps

Analogously to Example 5, pyrrolidinomethylene-glutacononitrile was cyclized with HCl gas. 2-Chloro-5-cyanopyridine was obtained in 83.3% of the theoretical yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05459273
Source datasetuspto-grants-1995_10
ORD IDord-c252468d73fa41afb7972ea6f97bc2b9
Source noteuspto-grants-1995_10