Diethyl Ether → HCID 10486868, compound

Participants

Reaction Steps

To a vigorously stirred mixture of the dithioketal from Step 6 (0.76 g) and CaCO3 (0.42 g) in THF (12 mL) and H2O (2.3 mL) was added in 10 min. a solution of mercury (II) perchlorate trihydrate (1.73 g; Aldrich) in H2O (1 mL). The mixture was stirred for 40 min. at r.t. before another portion of mercury salt solution (0.56 g in 0.2 mL of H2O) was slowly added. After 15 min., Et2O (50 mL) was added and the reaction mixture was filtered. The organic tiltrate was dried (MgSO4) and evaporated to afford the title ketone as an amber liquid.

Provenance & Evidence